R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

M2-polarized macrophages contribute to neovasculogenesis, leading to relapse of oral cancer following radiation
Authors: Makiko Okubo
Sci Rep, 2016;6(0):27548.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
A Lipid Based Antigen Delivery System Efficiently Facilitates MHC Class-I Antigen Presentation in Dendritic Cells to Stimulate CD8(+) T Cells
Authors: Mithun Maji
Sci Rep, 2016;6(0):27206.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
Nat Commun, 2016;7(0):11624.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus
Authors: Ahmed S Elshikha
PLoS ONE, 2016;11(5):e0156583.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response
Authors: Shweta Pasi
J Biol Chem, 2016;291(23):12358-69.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
p(70S6K1) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice.
Authors: Sasaki C, Chen G, Munk R, Eitan E, Martindale J, Longo D, Ghosh P
Eur J Immunol, 2016;46(1):212-22.

Role of interleukin-4, the chemokine CCL3 and its receptor CCR5 in neuropathic pain
Mol Immunol, 2016;77(0):184-192.
Species: Mouse
Sample Type: In Vivo
Application: In Vivo
Elastin-Derived Peptides Promote Abdominal Aortic Aneurysm Formation by Modulating M1/M2 Macrophage Polarization
J Immunol, 2016;196(11):4536-43.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Cutting Edge: Marginal Zone Macrophages Regulate Antigen Transport by B Cells to the Follicle in the Spleen via CD21
J Immunol, 2016;0(0):.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
Circ Res, 2016;0(0):.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
IL-12p40/IL-10 Producing preCD8?/Clec9A+ Dendritic Cells Are Induced in Neonates upon Listeria monocytogenes Infection
Authors: D Torres, A Köhler, S Delbauve, I Caminschi, MH Lahoud, K Shortman, V Flamand
PLoS Pathog, 2016;12(4):e1005561.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis
Authors: C Shimojima, H Takeuchi, S Jin, B Parajuli, H Hattori, A Suzumura, H Hibi, M Ueda, A Yamamoto
J Immunol, 2016;0(0):.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKC? Kinase Activity
Authors: E Naik, VM Dixit
J Immunol, 2016;196(8):3438-51.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Blockade of Extracellular ATP Effect by Oxidized ATP Effectively Mitigated Induced Mouse Experimental Autoimmune Uveitis (EAU)
PLoS ONE, 2016;11(5):e0155953.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
DNA-dependent protein kinase inhibition blocks asthma in mice and modulates human endothelial and CD4(+) T-cell function without causing severe combined immunodeficiency.
Authors: Ghonim M, Pyakurel K, Ju J, Rodriguez P, Lammi M, Davis C, Abughazleh M, Mansy M, Naura A, Boulares A
J Allergy Clin Immunol, 2015;135(2):425-40.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling.
Authors: Fleming B, Chandrasekaran P, Dillon L, Dalby E, Suresh R, Sarkar A, El-Sayed N, Mosser D
J Leukoc Biol, 2015;98(3):395-407.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Protease activity of Per a 10 potentiates Th2 polarization by increasing IL-23 and OX40L.
Authors: Agrawal K, Kale S, Arora N
Eur J Immunol, 2015;45(12):3375-85.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
B Cell-Intrinsic Expression of the HuR RNA-Binding Protein Is Required for the T Cell-Dependent Immune Response In Vivo.
Authors: DeMicco A, Naradikian M, Sindhava V, Yoon J, Gorospe M, Wertheim G, Cancro M, Bassing C
J Immunol, 2015;195(7):3449-62.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Cytokine-induced killer cells co-cultured with dendritic cells loaded with the protein lysate produced by radiofrequency ablation induce a specific antitumor response.
Authors: Shan, Chan-Cha, Shi, Liang-Ro, Ding, Mei-Qian, Zhu, Yi-Bei, Li, Xiao-Don, Xu, Bin, Jiang, Jing-Tin, Wu, Chang-Pi
Oncol Lett, 2015;9(4):1549-1556.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Novel mechanism of macrophage-mediated metastasis revealed in a zebrafish model of tumor development.
Authors: Wang J, Cao Z, Zhang X, Nakamura M, Sun M, Hartman J, Harris R, Sun Y, Cao Y
Cancer Res, 2015;75(2):306-15.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
IL-4 induces a suppressive IL-10-producing CD8+ T cell population via a Cdkn2a-dependent mechanism.
Authors: Zhao Y, Zhao H, Sun Y, Hao J, Qi X, Zhou X, Wu Z, Wang P, Kaech S, Weaver C, Flavell R, Zhao L, Yao Z, Yin Z
J Leukoc Biol, 2015;94(6):1103-12.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Redundant function of DNA ligase 1 and 3 in alternative end-joining during immunoglobulin class switch recombination.
Authors: Masani S, Han L, Meek K, Yu K
Proc Natl Acad Sci U S A, 2015;113(5):1261-6.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining.
Authors: Lu G, Duan J, Shu S, Wang X, Gao L, Guo J, Zhang Y
Proc Natl Acad Sci U S A, 2015;113(5):1256-60.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells.
Authors: Nakatsukasa H, Zhang D, Maruyama T, Chen H, Cui K, Ishikawa M, Deng L, Zanvit P, Tu E, Jin W, Abbatiello B, Goldberg N, Chen Q, Sun L, Zhao K, Chen W
Nat Immunol, 2015;16(10):1077-84.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
IRAK-M promotes alternative macrophage activation and fibroproliferation in bleomycin-induced lung injury.
Authors: Ballinger M, Newstead M, Zeng X, Bhan U, Mo X, Kunkel S, Moore B, Flavell R, Christman J, Standiford T
J Immunol, 2015;194(4):1894-904.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production.
Authors: Khairnar V, Duhan V, Maney S, Honke N, Shaabani N, Pandyra A, Seifert M, Pozdeev V, Xu H, Sharma P, Baldin F, Marquardsen F, Merches K, Lang E, Kirschning C, Westendorf A, Haussinger D, Lang F, Dittmer U, Kuppers R, Recher M, Hardt C, Scheffrahn I, Beauchemin N, Gothert J, Singer B, Lang P, Lang K
Nat Commun, 2015;6(0):6217.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity.
Authors: Sag D, Cekic C, Wu R, Linden J, Hedrick C
Nat Commun, 2015;6(0):6354.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.
Authors: Rutz S, Kayagaki N, Phung Q, Eidenschenk C, Noubade R, Wang X, Lesch J, Lu R, Newton K, Huang O, Cochran A, Vasser M, Fauber B, DeVoss J, Webster J, Diehl L, Modrusan Z, Kirkpatrick D, Lill J, Ouyang W, Dixit V
Nature, 2015;518(7539):417-21.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Inhibition of Ca2+-independent phospholipase A2beta (iPLA2beta) ameliorates islet infiltration and incidence of diabetes in NOD mice.
Authors: Bone R, Gai Y, Magrioti V, Kokotou M, Ali T, Lei X, Tse H, Kokotos G, Ramanadham S
Diabetes, 2015;64(2):541-54.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Constraints contributed by chromatin looping limit recombination targeting during Ig class switch recombination.
Authors: Feldman S, Achour I, Wuerffel R, Kumar S, Gerasimova T, Sen R, Kenter A
J Immunol, 2015;194(5):2380-9.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Glycogen Synthase Kinase-3beta (GSK-3beta) Inhibition Enhances Dendritic Cell-based Cancer Vaccine Potency via Suppression of Interferon-gamma-induced Indoleamine 2,3-Dioxygenase Expression.
Authors: Noh K, Son K, Jung I, Kang T, Choi C, Park Y
J Biol Chem, 2015;290(19):12394-402.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-beta using BV2 microglial cells and APP/PS1 transgenic mice.
Authors: Latta C, Sudduth T, Weekman E, Brothers H, Abner E, Popa G, Mendenhall M, Gonzalez-Oregon F, Braun K, Wilcock D
J Neuroinflammation, 2015;12(0):41.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Radiation-driven lipid accumulation and dendritic cell dysfunction in cancer.
Authors: Gao F, Liu C, Guo J, Sun W, Xian L, Bai D, Liu H, Cheng Y, Li B, Cui J, Zhang C, Cai J
Sci Rep, 2015;5(0):9613.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Immunosuppression in early postnatal days induces persistent and allergen-specific immune tolerance to asthma in adult mice.
Authors: Chen, Yan, Zhang, Jin, Lu, Yong, Wang, Libo
PLoS ONE, 2015;10(4):e0122990.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Concentrated protein body product derived from rice endosperm as an oral tolerogen for allergen-specific immunotherapy--a new mucosal vaccine formulation against Japanese cedar pollen allergy.
Authors: Wakasa Y, Takagi H, Watanabe N, Kitamura N, Fujiwara Y, Ogo Y, Hayashi S, Yang L, Ohta M, Thet Tin W, Sekikawa K, Takano M, Ozawa K, Hiroi T, Takaiwa F
PLoS ONE, 2015;10(3):e0120209.
Species: Mouse
Sample Type: In Vivo

Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation.
Authors: Dingler F, Kemmerich K, Neuberger M, Rada C
Eur J Immunol, 2014;44(7):1925-35.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
DMXAA causes tumor site-specific vascular disruption in murine non-small cell lung cancer, and like the endogenous non-canonical cyclic dinucleotide STING agonist, 2'3'-cGAMP, induces M2 macrophage repolarization.
Authors: Downey C, Aghaei M, Schwendener R, Jirik F
PLoS ONE, 2014;9(6):e99988.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
TRAF5 negatively regulates TLR signaling in B lymphocytes.
Authors: Buchta C, Bishop G
J Immunol, 2014;192(1):145-50.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
Authors: Ramkhelawon B, Hennessy E, Menager M, Ray T, Sheedy F, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner K, Moore K
Nat Med, 2014;20(4):377-84.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Failed renoprotection by alternatively activated bone marrow macrophages is due to a proliferation-dependent phenotype switch in vivo.
Authors: Cao Q, Wang Y, Zheng D, Sun Y, Wang C, Wang X, Lee V, Wang Y, Zheng G, Tan T, Wang Y, Alexander S, Harris D
Kidney Int, 2014;85(4):794-806.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
A role for the ITAM signaling module in specifying cytokine-receptor functions.
Authors: Bezbradica J, Rosenstein R, DeMarco R, Brodsky I, Medzhitov R
Nat Immunol, 2014;15(4):333-42.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma.
Authors: Shibata T, Habiel D, Coelho A, Kunkel S, Lukacs N, Hogaboam C
J Immunol, 2014;192(8):3569-81.
Species: Mouse
Sample Type: Tissue Homogenates
Application: Luminex standard
MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity.
Authors: Benasciutti E, Mariani E, Oliva L, Scolari M, Perilli E, Barras E, Milan E, Orfanelli U, Fazzalari N, Campana L, Capobianco A, Otten L, Particelli F, Acha-Orbea H, Baruffaldi F, Faccio R, Sitia R, Reith W, Cenci S
J Bone Miner Res, 2014;29(2):290-303.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Accelerated neurodegeneration and neuroinflammation in transgenic mice expressing P301L tau mutant and tau-tubulin kinase 1.
Authors: Asai H, Ikezu S, Woodbury M, Yonemoto G, Cui L, Ikezu T
Am J Pathol, 2014;184(3):808-18.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Colony-stimulating factor-1 signaling suppresses renal crystal formation.
Authors: Taguchi K, Okada A, Kitamura H, Yasui T, Naiki T, Hamamoto S, Ando R, Mizuno K, Kawai N, Tozawa K, Asano K, Tanaka M, Miyoshi I, Kohri K
J Am Soc Nephrol, 2014;25(8):1680-97.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Binding of AID to DNA does not correlate with mutator activity.
Authors: Matthews A, Husain S, Chaudhuri J
J Immunol, 2014;193(1):252-7.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Glucose-dependent de novo lipogenesis in B lymphocytes: a requirement for atp-citrate lyase in lipopolysaccharide-induced differentiation.
Authors: Dufort, Fay J, Gumina, Maria R, Ta, Nathan L, Tao, Yongzhen, Heyse, Shannon, Scott, David A, Richardson, Adam D, Seyfried, Thomas N, Chiles, Thomas C
J Biol Chem, 2014;289(10):7011-24.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice.
Authors: Park J, Lim M, Cho M, Ryu J, Moon Y, Jhun J, Byun J, Kim E, Hwang S, Ju J, Kwok S, Kim H
Arthritis Rheum, 2013;65(4):949-59.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Antigen-specific induced T regulatory cells impair dendritic cell function via an IL-10/MARCH1-dependent mechanism.
Authors: Chattopadhyay, Gouri, Shevach, Ethan M
J Immunol, 2013;191(12):5875-84.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
The exonuclease Trex1 restrains macrophage proinflammatory activation.
Authors: Pereira-Lopes S, Celhar T, Sans-Fons G, Serra M, Fairhurst A, Lloberas J, Celada A
J Immunol, 2013;191(12):6128-35.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Functional education of invariant NKT cells by dendritic cell tuning of SHP-1.
Authors: Napolitano, Anna, Pittoni, Paola, Beaudoin, Lucie, Lehuen, Agnes, Voehringer, David, MacDonald, H Robson, Dellabona, Paolo, Casorati, Giulia
J Immunol, 2013;190(7):3299-308.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Inflammasome adaptor protein Apoptosis-associated speck-like protein containing CARD (ASC) is critical for the immune response and survival in west Nile virus encephalitis.
Authors: Kumar M, Roe K, Orillo B, Muruve D, Nerurkar V, Gale M, Verma S
J Virol, 2013;87(7):3655-67.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination.
Authors: Lam T, Thomas L, White C, Li G, Pone E, Xu Z, Casali P
PLoS ONE, 2013;8(11):e80414.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Mouse BAZ1A (ACF1) is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis.
Authors: Dowdle J, Mehta M, Kass E, Vuong B, Inagaki A, Egli D, Jasin M, Keeney S
PLoS Genet, 2013;9(11):e1003945.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
TNF-like ligand 1A (TL1A) gene knockout leads to ameliorated collagen-induced arthritis in mice: implication of TL1A in humoral immune responses.
Authors: Wang X, Hu Y, Charpentier T, Lamarre A, Qi S, Wu J, Luo H
J Immunol, 2013;191(11):5420-9.
Species: Mouse
Sample Type: cells
Application: cell culture
Breast regression protein-39 (BRP-39) promotes dendritic cell maturation in vitro and enhances Th2 inflammation in murine model of asthma.
Authors: Xu Q, Chai S, Qian Y, Zhang M, Wang K
Acta Pharmacol Sin, 2012;33(12):1525-32.
Species: Mouse
Sample Type: whole cells
Application: Cell Culture Substrate
Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands.
Authors: Munich S, Sobo-Vujanovic A, Buchser W, Beer-Stolz D, Vujanovic N
Oncoimmunology, 2012;1(7):1074-1083.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Protein kinase C delta (PKCdelta)-extracellular signal-regulated kinase 1/2 (ERK1/2) signaling cascade regulates glycogen synthase kinase-3 (GSK-3) inhibition-mediated interleukin-10 (IL-10) expression in lipopolysaccharide (LPS)-induced endotoxemia.
Authors: Noh KT, Son KH, Jung ID, Kang HK, Hwang SA, Lee WS, You JC, Park YM
J. Biol. Chem., 2012;287(17):14226-33.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
An epigenetic silencing pathway controlling T helper 2 cell lineage commitment.
Authors: Allan RS, Zueva E, Cammas F, Schreiber HA, Masson V, Belz GT, Roche D, Maison C, Quivy JP, Almouzni G, Amigorena S
Nature, 2012;487(7406):249-53.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
CCL25 induces alpha 4 beta 7 integrin-dependent migration of IL-17+ gamma/delta T lymphocytes during an allergic reaction.
Authors: Costa MF, Bornstein VU, Candea AL, Henriques-Pons A, Henriques MG, Penido C
Eur. J. Immunol., 2012;42(5):1250-60.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Regulation of innate CD8+ T-cell activation mediated by cytokines.
Proc Natl Acad Sci U S A, 2012;109(25):9971-6.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells.
Nat. Med., 2012;1248(0):18.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
The MSHA Strain of Pseudomonas Aeruginosa Activated TLR Pathway and Enhanced HIV-1 DNA Vaccine Immunoreactivity.
Authors: Hou J, Liu Y, Liu Y, Shao Y
PLoS ONE, 2012;7(10):e47724.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
TNFR-Associated Factor 2 Deficiency in B Lymphocytes Predisposes to Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma in Mice.
Authors: Perez-Chacon G, Llobet D, Pardo C, Pindado J, Choi Y, Reed JC, Zapata JM
J. Immunol., 2012;189(2):1053-61.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and function.
Authors: Jin W, Qi S, Luo H
BMC Immunol., 2011;12(0):68.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Sustained signaling by canonical helper T cell cytokines throughout the reactive lymph node.
Authors: Perona-Wright G, Mohrs K, Mohrs M
Nat. Immunol., 2010;11(6):520-6.
Species: Mouse
Sample Type: In Vivo
Application: In Vivo
The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.
Authors: Chang HC, Sehra S, Goswami R, Yao W, Yu Q, Stritesky GL, Jabeen R, McKinley C, Ahyi AN, Han L, Nguyen ET, Robertson MJ, Perumal NB, Tepper RS, Nutt SL, Kaplan MH
Nat. Immunol., 2010;11(6):527-34.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus.
Authors: Kayamuro H, Yoshioka Y, Abe Y, Arita S, Katayama K, Nomura T, Yoshikawa T, Kubota-Koketsu R, Ikuta K, Okamoto S, Mori Y, Kunisawa J, Kiyono H, Itoh N, Nagano K, Kamada H, Tsutsumi Y, Tsunoda S
J. Virol., 2010;84(24):12703-12.
Species: Mouse
Sample Type: In Vivo
Application: In Vivo
Oncostatin M induces dendritic cell maturation and Th1 polarization.
Authors: Jung ID, Noh KT, Lee CM, Chun SH, Jeong SK, Park JW, Park WS, Kim HW, Yun CH, Shin YK, Park YM
Biochem. Biophys. Res. Commun., 2010;394(2):272-8.
Species: Mouse
Sample Type: Whole Cells
Application: Media Supplement - Cell Prep
Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
Authors: Yoshizaki A, Yanaba K, Iwata Y
J. Immunol., 2010;185(4):2502-15.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages.
Authors: Filardy AA, Pires DR, Nunes MP, Takiya CM, Freire-de-Lima CG, Ribeiro-Gomes FL, DosReis GA
J. Immunol., 2010;185(4):2044-50.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.
Authors: Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW
Mucosal Immunol, 2010;3(1):40-8.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
PEGylation of interleukin-10 for the mitigation of enhanced pain states.
Authors: Soderquist RG, Milligan ED, Harrison JA, Chavez RA, Johnson KW, Watkins LR, Mahoney MJ
J Biomed Mater Res A, 2010;93(3):1169-79.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis.
Authors: Wieland CW, van der Windt GJ, Florquin S, McKenzie AN, van der Poll T
Microbes Infect., 2009;11(4):524-30.

TLR4 ligands induce IFN-alpha production by mouse conventional dendritic cells and human monocytes after IFN-beta priming.
Authors: Richez C, Yasuda K, Watkins AA
J. Immunol., 2009;182(2):820-8.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells.
Authors: Dienz O, Eaton SM, Bond JP, Neveu W, Moquin D, Noubade R, Briso EM, Charland C, Leonard WJ, Ciliberto G, Teuscher C, Haynes L, Rincon M
J. Exp. Med., 2009;206(1):69-78.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation.
Authors: Claudio E, Sonder SU, Saret S, Carvalho G, Ramalingam TR, Wynn TA, Chariot A, Garcia-Perganeda A, Leonardi A, Paun A, Chen A, Ren NY, Wang H, Siebenlist U
J. Immunol., 2009;182(3):1617-30.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Controlled delivery of T-box21 small interfering RNA ameliorates autoimmune alopecia (Alopecia Areata) in a C3H/HeJ mouse model.
Authors: Nakamura M, Jo J, Tabata Y, Ishikawa O
Am. J. Pathol., 2008;172(3):650-8.
Species: Mouse
Sample Type: In Vivo
Application: In Vivo
A mechanism for the initiation of allergen-induced T helper type 2 responses.
Authors: Sokol CL, Barton GM, Farr AG, Medzhitov R
Nat. Immunol., 2008;9(3):310-8.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Interferon-gamma limits Th1 lymphocyte adhesion to inflamed endothelium: a nitric oxide regulatory feedback mechanism.
Authors: Norman MU, Zbytnuik L, Kubes P
Eur. J. Immunol., 2008;38(5):1368-80.
Species: Mouse
Sample Type: In Vivo
Application: In Vivo
TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice.
Authors: McKinley L, Alcorn JF, Peterson A, Dupont RB, Kapadia S, Logar A, Henry A, Irvin CG, Piganelli JD, Ray A, Kolls JK
J. Immunol., 2008;181(6):4089-97.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis.
Authors: Wieland CW, van der Windt GJ, Wiersinga WJ, Florquin S, van der Poll T
Immunology, 2008;125(2):272-9.
Species: N/A
Sample Type: N/A
Application: ELISA Standard
Direct B cell stimulation by dendritic cells in a mouse model of lupus.
Authors: Wan S, Zhou Z, Duan B, Morel L
Arthritis Rheum., 2008;8(0):1741-50.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Adenosine receptors in regulation of dendritic cell differentiation and function.
Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM
Blood, 2008;112(5):1822-31.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa, functions as a T helper cell modulator.
Authors: Chiang YM, Chang CL, Chang SL, Yang WC, Shyur LF
J Ethnopharmacol, 2007;110(3):532-8.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Interleukin-4 does not influence development of hypercholesterolemia or angiotensin II-induced atherosclerotic lesions in mice.
Authors: King VL, Cassis LA, Daugherty A
Am. J. Pathol., 2007;171(6):2040-7.
Species: Mouse
Sample Type: In Vivo
Application: In Vivo
In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation.
Authors: Seshasayee D, Lee WP, Zhou M, Shu J, Suto E, Zhang J, Diehl L, Austin CD, Meng YG, Tan M, Bullens SL, Seeber S, Fuentes ME, Labrijn AF, Graus YM, Miller LA, Schelegle ES, Hyde DM, Wu LC, Hymowitz SG, Martin F
J. Clin. Invest., 2007;117(12):3868-3878.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
The IL-4/IL-13/Stat6 signalling pathway promotes luminal mammary epithelial cell development.
Authors: Khaled WT, Read EK, Nicholson SE, Baxter FO, Brennan AJ, Came PJ, Sprigg N, McKenzie AN, Watson CJ
Development, 2007;134(15):2739-50.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Dendritic cells loaded with apoptotic antibody-coated tumor cells provide protective immunity against B-cell lymphoma in vivo.
Authors: Franki SN, Steward KK, Betting DJ, Kafi K, Yamada RE, Timmerman JM
Blood, 2007;111(3):1504-11.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
The JAK-3 inhibitor CP-690550 is a potent anti-inflammatory agent in a murine model of pulmonary eosinophilia.
Authors: Kudlacz E, Conklyn M, Andresen C, Whitney-Pickett C, Changelian P
Eur. J. Pharmacol., 2007;582(1):154-61.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells.
Authors: Zheng SG, Wang J, Wang P, Gray JD, Horwitz DA
J. Immunol., 2007;178(4):2018-27.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
The 130-kDa glycoform of CD43 functions as an E-selectin ligand for activated Th1 cells in vitro and in delayed-type hypersensitivity reactions in vivo.
Authors: Alcaide P, King SL, Dimitroff CJ, Lim YC, Fuhlbrigge RC, Luscinskas FW
J. Invest. Dermatol., 2007;127(8):1964-72.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines.
Authors: Koya RC, Kimura T, Ribas A, Rozengurt N, Lawson GW, Faure-Kumar E, Wang HJ, Herschman H, Kasahara N, Stripecke R
Mol. Ther., 2007;15(5):971-80.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
Immunity, 2007;26(4):445-59.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Critical role of the Fc receptor gamma-chain on APCs in the development of allergen-induced airway hyperresponsiveness and inflammation.
Authors: Kitamura K, Takeda K, Koya T, Miyahara N, Kodama T, Dakhama A, Takai T, Hirano A, Tanimoto M, Harada M, Gelfand EW
J. Immunol., 2007;178(1):480-8.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance.
Authors: Zelante T, De Luca A, Bonifazi P, Montagnoli C, Bozza S, Moretti S, Belladonna ML, Vacca C, Conte C, Mosci P, Bistoni F, Puccetti P, Kastelein RA, Kopf M, Romani L
Eur. J. Immunol., 2007;37(10):2695-706.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Liposomal retinoic acids modulate asthma manifestations in mice.
Authors: Maret M, Ruffie C, Periquet B, Campo AM, Menevret M, Phelep A, Dziewiszek K, Druilhe A, Pretolani M
J. Nutr., 2007;137(12):2730-6.
Species: N/A
Sample Type: N/A
Application: ELISA Standard
T-bet inhibits both TH2 cell-mediated eosinophil recruitment and TH17 cell-mediated neutrophil recruitment into the airways.
Authors: Fujiwara M, Hirose K, Kagami S, Takatori H, Wakashin H, Tamachi T, Watanabe N, Saito Y, Iwamoto I, Nakajima H
J. Allergy Clin. Immunol., 2007;119(3):662-70.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
The endothelial cell-produced antiangiogenic cytokine vascular endothelial growth inhibitor induces dendritic cell maturation.
Authors: Tian F, Grimaldo S, Fujita M, Fugita M, Cutts J, Vujanovic NL, Li LY
J. Immunol., 2007;179(6):3742-51.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Severe sepsis exacerbates cell-mediated immunity in the lung due to an altered dendritic cell cytokine profile.
Authors: Wen H, Hogaboam CM, Gauldie J, Kunkel SL
Am. J. Pathol., 2006;168(6):1940-50.
Species: N/A
Sample Type: N/A
Application: ELISA Standard
Activin A functions as a Th2 cytokine in the promotion of the alternative activation of macrophages.
Authors: Ogawa K, Funaba M, Chen Y, Tsujimoto M
J. Immunol., 2006;177(10):6787-94.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis.
Authors: Butovsky O, Landa G, Kunis G, Ziv Y, Avidan H, Greenberg N, Schwartz A, Smirnov I, Pollack A, Jung S, Schwartz M
J. Clin. Invest., 2006;116(4):905-15.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation.
Authors: Liu Q, Chen T, Chen G, Li N, Wang J, Ma P, Cao X
Biochem. Biophys. Res. Commun., 2006;345(3):1122-30.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells.
Authors: Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar AE, Pluchino S, Martino G, Schwartz M
Mol. Cell. Neurosci., 2006;31(1):149-60.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Cytokine milieu of atopic dermatitis skin subverts the innate immune response to vaccinia virus.
Authors: Howell MD, Gallo RL, Boguniewicz M, Jones JF, Wong C, Streib JE, Leung DY
Immunity, 2006;24(3):341-8.
Species: Mouse
Sample Type: In Vivo
Application: In Vivo
3BP2 deficiency impairs the response of B cells, but not T cells, to antigen receptor ligation.
Authors: de la Fuente MA, Kumar L, Lu B, Geha RS
Mol. Cell. Biol., 2006;26(14):5214-25.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.
Authors: Wada A, Tada Y, Shimozato O, Takiguchi Y, Tatsumi K, Kuriyama T, Tagawa M
Anticancer Res., 2005;25(1):299-303.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages.
Authors: Harrington, Laurie E, Hatton, Robin D, Mangan, Paul R, Turner, Henriett, Murphy, Theresa, Murphy, Kenneth, Weaver, Casey T
Nat Immunol, 2005;6(11):1123-32.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
IL-1 mediates TNF-induced osteoclastogenesis.
Authors: Wei S, Kitaura H, Zhou P, Ross FP, Teitelbaum SL
J. Clin. Invest., 2005;115(2):282-90.
Species: Human
Sample Type: Whole Cells
Application: Bioassay
Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation.
Authors: Dikov MM, Ohm JE, Ray N, Tchekneva EE, Burlison J, Moghanaki D, Nadaf S, Carbone DP
J. Immunol., 2005;174(1):215-22.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Control of Leishmania major in the absence of Tyk2 kinase.
Authors: Schleicher U, Mattner J, Blos M, Schindler H, Rollinghoff M, Karaghiosoff M, Muller M, Werner-Felmayer G, Bogdan C
Eur. J. Immunol., 2004;34(2):519-29.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs.
Authors: Borg C, Jalil A, Laderach D, Maruyama K, Wakasugi H, Charrier S, Ryffel B, Cambi A, Figdor C, Vainchenker W, Galy A, Caignard A, Zitvogel L
Blood, 2004;104(10):3267-75.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow.
Authors: Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP
J. Immunol., 2004;172(12):7408-16.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Dual roles of IL-4 in lung injury and fibrosis.
Authors: Huaux F, Liu T, McGarry B, Ullenbruch M, Phan SH
J. Immunol., 2003;170(4):2083-92.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Intracellular thiols contribute to Th2 function via a positive role in IL-4 production.
Authors: Monick MM, Samavati L, Butler NS, Mohning M, Powers LS, Yarovinsky T, Spitz DR, Hunninghake GW
J. Immunol., 2003;171(10):5107-15.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
P-selectin mediates IL-13-induced eosinophil transmigration but not eotaxin generation in vivo: a comparative study with IL-4-elicited responses.
Authors: Larbi KY, Dangerfield JP, Culley FJ, Marshall D, Haskard DO, Jose PJ, Williams TJ, Nourshargh S
J. Leukoc. Biol., 2003;73(1):65-73.
Species: Mouse
Sample Type: In Vivo
Application: In Vivo
AMD3100, a CxCR4 antagonist, attenuates allergic lung inflammation and airway hyperreactivity.
Authors: Lukacs NW, Berlin A, Schols D, Skerlj RT, Bridger GJ
Am. J. Pathol., 2002;160(4):1353-60.
Species: N/A
Sample Type: N/A
Application: ELISA Standard
Cytokine production by mouse myeloid dendritic cells in relation to differentiation and terminal maturation induced by lipopolysaccharide or CD40 ligation.
Authors: Morelli AE, Zahorchak AF, Larregina AT
Blood, 2001;98(5):1512-23.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
The IL-6 family cytokines, interleukin-6, interleukin-11, oncostatin M, and leukemia inhibitory factor, enhance mast cell growth through fibroblast-dependent pathway in mice.
Authors: Gyotoku E, Morita E, Kameyoshi Y, Hiragun T, Yamamoto S, Hide M
Arch. Dermatol. Res., 2001;293(10):508-14.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay
Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function.
Authors: Gabrilovich DI, Ishida T, Nadaf S, Ohm JE, Carbone DP
Clin. Cancer Res., 1999;5(10):2963-70.
Species: Mouse
Sample Type: Whole Cells
Application: Bioassay

rmIL-4, CF (1 MG)